Epithelial growth over the optic surface of the type 1 Boston Keratoprosthesis: histopathology and implications for biointegration
نویسندگان
چکیده
We report the histopathology of epithelial overgrowth in the Boston type I keratoprosthesis. The epithelium shows an inconsistent number of layers and basement membrane and goblet cells are absent. Epithelialization of the keratoprosthesis optic would have multiple advantages, but the limitation of vision makes tolerating the overgrowth difficult.
منابع مشابه
[Keratoprosthesis in cornea and ocular surface diseases].
In 1771, Guillaume Pellier de Quengsy,1 an ophthalmologist, proposed for the first time the possibility of substituting opacifie corneal tissue by “an artificial cornea”. The proposal was for transparent glass plates to substitute the opaque cornea in order to enhance the transparency of optic media. Improvements in topical and systemic immunosuppression and limbus transplant techniques for tre...
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AIMS To report the histological findings in two AlphaCor artificial corneas explanted following complications,to compare the mechanism of biointegration and/or failure of the device and the correlation with clinical histories. METHODS The first patient was diagnosed with optic deposits and corneal melting during the late postoperative period and required the removal of the device. The second ...
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Purpose To report the outcomes of implantation of the Boston Type I keratoprosthesis in three patients with Acanthamoeba keratitis (AK), a severe infection that can lead to significant visual loss. Observations Case series reporting three patients with difficult cases of AK that needed multiple corneal transplantations and glaucoma surgeries. All patients were implanted with the Boston Type I...
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PURPOSE To evaluate the anterior keratoprosthesis-cornea interface in eyes with Boston type I keratoprosthesis (Kpro). METHODS In a prospective non-interventional study, patients with Boston type I Kpro underwent ultra-high resolution optical coherence tomography (UHR-OCT) evaluation. The images were used to measure and describe characteristics of the anterior keratoprosthesis-cornea interfac...
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